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Article

Distribution of PON1 polymorphisms PON1Q192R and PON1L55M among Chinese, Malay and Indian males in Singapore and possible susceptibility to organophosphate exposure.

Neurotoxicology - 1 Mar 2009

Chia Sin Eng, Mohamed Ali Safiyya, Yap Peng Huat Eric, Gan Linda, Ong Yeong Bing, Chia Kee Seng

Abstract excerpt

Organophosphate (OP)-containing pesticides are widely used worldwide for domestic and industrial purposes. Studies on acute and chronic exposure to OPs have revealed numerous health effects attributed mainly to acetylcholinesterase (AChE) inhibition. The enzyme human serum paraoxonase (PON1) is involved in the detoxification of OP compounds. PON1 polymorphisms have been shown to affect susceptibility to OP...

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Source

Identifiers

PMID: 19135476
DOI: 10.1016/j.neuro.2008.12.004

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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