Article
Human serum paraoxonase (PON1) activity in acute organophosphorous insecticide poisoning.
Forensic science international - 23 Apr 2003
Akgür S A, Oztürk P, Solak I, Moral A R, Ege B
Abstract excerpt
Human serum paraoxonase (PON1) and perhaps other mammalian paraoxonases catalyzes the hydrolysis of certain organophosphorus (OP) insecticides and nerve gases and so may alter significantly an individual's susceptibility to the toxicity of these chemicals. Serum PON1 exhibits a substrate dependent polymorphism and this polymorphism shows great interethnic variability. This study focused on the investigation of...
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