Article
Isoniazid resistance and the future of drug-resistant tuberculosis.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2004
Cohen Ted, Becerra Mercedes C, Murray Megan B
Abstract excerpt
Bacterial chromosomal mutations that confer antibiotic resistance often have deleterious effects that impose costs on reproductive fitness. This observation has led to the generalization that in the absence of the selection pressure exerted through treatment, the frequency of resistance will decrease. This model implies that the prudent use of antibiotics will eventually result in a decline in the prevalence of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.