Chromosomal deletions and K-ras gene mutations in human endometrial carcinomas.

doi:10.1002/ijc.2910510110

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Article

Chromosomal deletions and K-ras gene mutations in human endometrial carcinomas.

International journal of cancer - 22 Apr 1992

Imamura T, Arima T, Kato H, Miyamoto S, Sasazuki T, Wake N

Abstract excerpt

Forty-two endometrial carcinomas of various stages of progression were analyzed to search for loss of chromosomal regions and for point mutations of ras genes and amplification of Int-2 gene. This approach is particularly favorable for observation of genetic events and their significance in the p...

Topics

Adult
Aged
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 18
Endometrial Neoplasms
Female
Gene Amplification
Genes, Suppressor
Genes, ras
Humans
Middle Aged
Mutation
Nucleic Acid Hybridization

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