Article
Chromosomal deletions and K-ras gene mutations in human endometrial carcinomas.
International journal of cancer - 22 Apr 1992
Imamura T, Arima T, Kato H, Miyamoto S, Sasazuki T, Wake N
Abstract excerpt
Forty-two endometrial carcinomas of various stages of progression were analyzed to search for loss of chromosomal regions and for point mutations of ras genes and amplification of Int-2 gene. This approach is particularly favorable for observation of genetic events and their significance in the process of neoplastic conversion by considering the clinico-pathological characteristics of each tumor. At least 3...
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