Deletions of 17p are associated with transition from early to advanced colorectal cancer.

doi:10.1016/s0165-4608(03)00188-2

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Deletions of 17p are associated with transition from early to advanced colorectal cancer.

Cancer genetics and cytogenetics - 1 Nov 2003

Risio Mauro, Casorzo Laura, Chiecchio Laura, De Rosa Giovanni, Rossini Francesco Paolo

Abstract excerpt

Several chromosome defects parallel morphologic evolution in colorectal tumor progression. Allelic losses in the short arm of chromosome 17, the majority encompassing the 17p13.3 band, have been found in advanced cancer in the absence of TP53 mutations, suggesting that loss of genes in this chromosome region is relevant for tumorigenesis. The aim of this study was to investigate 17p13.3 deletions throughout the...

Topics

Adenocarcinoma
Chromosome Aberrations
Chromosome Deletion
Chromosomes, Human, Pair 17
Colonic Neoplasms
Disease Progression
Genes, p53
Humans
In Situ Hybridization, Fluorescence
Intestinal Mucosa
Mutation
Neoplasm Staging
Rectal Neoplasms
Sigmoid Neoplasms

Source

Open in PubMed

Identifiers

PMID: 14580770
DOI: 10.1016/s0165-4608(03)00188-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics