Article
Allelic loss and prognosis in carcinoma of the uterine cervix.
International journal of cancer - 21 Aug 1998
Kersemaekers A M, Kenter G G, Hermans J, Fleuren G J, van de Vijver M J
Abstract excerpt
Cervical carcinomas develop as a result of multiple genetic alterations. As the genetic alterations are the cause of malignant transformation, it is likely that specific genetic alterations lead to specific clinical behaviour. The aim of this study was (i) to localise chromosome arms that harbour likely tumour-suppressor genes, by analysing loss of heterozygosity (LOH) and (ii) to study the association of LOH...
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