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Article

Genomic alterations in human breast carcinomas.

Genes, chromosomes & cancer - 1 Sept 1990

Larsson C, Byström C, Skoog L, Rotstein S, Nordenskjöld M

Abstract excerpt

All human chromosomes were screened in 52 human breast carcinomas for the occurrence of allele losses, in order to identify genomic alterations involved in initiation and progression of the disease. Loss of chromosome 22 alleles was detected in 6 out of 8 lobular carcinomas, while chromosome 17 losses were most frequent in ductal carcinomas. Furthermore, patients who developed advanced disease after many years of...

Topics

Adenocarcinoma, Mucinous
Alleles
Blotting, Southern
Breast Neoplasms
Carcinoma
Carcinoma, Intraductal, Noninfiltrating
Carcinoma, Papillary
Chromosome Deletion
DNA, Neoplasm
Female
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mutation

Neoplasm Metastasis

Nucleic Acid Hybridization

Source

Identifiers

PMID: 1964080
DOI: 10.1002/gcc.2870020305

Genes

ERBB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1964080-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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