Loss of heterozygosity and K-ras gene mutations in gastric cancer.

doi:10.1007/BF00244466

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Article

Loss of heterozygosity and K-ras gene mutations in gastric cancer.

Human genetics - 1 Oct 1993

Ranzani G N, Renault B, Pellegata N S, Fattorini P, Magni E, Bacci F, Amadori D

Abstract excerpt

In order to identify relevant genetic lesions in gastric carcinoma, we searched for tumor suppressor gene inactivation and K-ras gene mutations by analyzing tumor and control DNAs from 34 patients. These were from an epidemiologically defined area of Italy characterized by one of the world's high...

Topics

Alleles
Blotting, Southern
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 18
Chromosomes, Human, Pair 5
Chromosomes, Human, Pair 7
DNA Mutational Analysis
Electrophoresis, Polyacrylamide Gel
Gene Deletion
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor
Genes, ras
Genetic Markers
Heterozygote
Humans
Italy

Source

Open in PubMed

Identifiers

PMID: 8406432
DOI: 10.1007/BF00244466

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8406432-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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