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Article

Loss of heterozygosity and K-ras gene mutations in gastric cancer.

Human genetics - 1 Oct 1993

Ranzani G N, Renault B, Pellegata N S, Fattorini P, Magni E, Bacci F, Amadori D

Abstract excerpt

In order to identify relevant genetic lesions in gastric carcinoma, we searched for tumor suppressor gene inactivation and K-ras gene mutations by analyzing tumor and control DNAs from 34 patients. These were from an epidemiologically defined area of Italy characterized by one of the world's highest incidences of stomach cancer. Allele losses were investigated by the Southern blotting procedure at 16 polymorphic...

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PMID: 8406432
DOI: 10.1007/BF00244466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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