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Article

DCC gene alteration in human endometrial carcinomas.

International journal of cancer - 15 May 1994

Gima T, Kato H, Honda T, Imamura T, Sasazuki T, Wake N

Abstract excerpt

The present study was undertaken to define the gene(s) of importance on the long arm of chromosome 18 (chromosome 18q) in endometrial carcinomas. We analyzed loss of heterozygosity (LOH) at 3 loci on chromosome 18q and DCC gene expression by the reverse-transcriptase/polymerase chain reaction (RT-PCR) method. Among 61 tumors that were informative, 16 (26%), estimated to be a minimum number, showed allelic losses...

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Source

Identifiers

PMID: 7514150
DOI: 10.1002/ijc.2910570407

Genes

DCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DCC gene alteration in human endometrial carcinomas.PMID 7514150Read ↗

Identification of a chromosome 18q gene that is altered in colorectal cancers.Semantic proximity Read ↗

Frequent allelic deletions and loss of expression characterize the DCC gene in male germ cell tumors.Semantic proximity Read ↗

Involvement of mutations in the DPC4 promoter in endometrial carcinoma development.Semantic proximity Read ↗

Mutation and expression of the DCC gene in human lung cancer.Semantic proximity Read ↗

Expression and mutational analysis of the DCC, DPC4, and MADR2/JV18-1 genes in neuroblastoma.Semantic proximity Read ↗

Frequent loss of expression without sequence mutations of the DCC gene in primary gastric cancer.Semantic proximity Read ↗

Somatic genetic changes on chromosome 18 in breast carcinomas: is the DCC gene involved?Semantic proximity Read ↗

Allele loss from 5q21 (APC/MCC) and 18q21 (DCC) and DCC mRNA expression in breast cancer.Semantic proximity Read ↗

Mapping of a breast cancer tumor suppressor gene locus to a 4-cM interval on chromosome 18q21.Semantic proximity Read ↗

The DCC Protein and Prognosis in Colorectal CancerSemantic proximity Read ↗

Chromosomal deletions and K-ras gene mutations in human endometrial carcinomas.Semantic proximity Read ↗

Lower frequency of allele loss on chromosome 18q in human breast cancer than in colorectal tumors.Semantic proximity Read ↗

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