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Article

Genetic and epigenetic alteration of the NF2 gene in sporadic meningiomas.

Genes, chromosomes & cancer - 1 Mar 2005

Lomas Jesus, Bello M Josefa, Arjona Dolores, Alonso M Eva, Martinez-Glez Victor, Lopez-Marin Isabel, Amiñoso Cinthia, de Campos Jose M, Isla Alberto, Vaquero Jesus, Rey Juan A

Abstract excerpt

The role of the NF2 gene in the development of meningiomas has recently been documented; inactivating mutations plus allelic loss at 22q, the site of this gene (at 22q12), have been identified in both sporadic and neurofibromatosis type 2-associated tumors. Although epigenetic inactivation through aberrant CpG island methylation of the NF2 5' flanking region has been documented in schwannoma (another...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 15609345
DOI: 10.1002/gcc.20141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic and epigenetic alteration of the NF2 gene in sporadic meningiomas.PMID 15609345Read ↗

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