Combined molecular genetic studies of chromosome 22q and the neurofibromatosis type 2 gene in central nervous system tumors.

doi:10.1227/00006123-199510000-00022

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Article

Combined molecular genetic studies of chromosome 22q and the neurofibromatosis type 2 gene in central nervous system tumors.

Neurosurgery - 1 Oct 1995

Ng H K, Lau K M, Tse J Y, Lo K W, Wong J H, Poon W S, Huang D P

Abstract excerpt

Monosomy of chromosome 22 or deletions of 22q have been described in meningiomas and astrocytic tumors, the incidence of which is increased in Type 2 neurofibromatosis. Recently, the gene for neurofibromatosis Type 2 (NF2) has been identified at Chromosome 22q12, and a tumor suppression role has...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Astrocytoma
Brain
Brain Neoplasms
Cell Transformation, Neoplastic
Central Nervous System Neoplasms
Child
Chromosome Aberrations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Chromosome Deletion

Chromosome Disorders

Chromosomes, Human, Pair 22

DNA Mutational Analysis

Exons

Female

Source

Open in PubMed

Identifiers

PMID: 8559307
DOI: 10.1227/00006123-199510000-00022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8559307-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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