Article
NF2 gene mutations and allelic status of 1p, 14q and 22q in sporadic meningiomas.
Oncogene - 1 Apr 1999
Leone P E, Bello M J, de Campos J M, Vaquero J, Sarasa J L, Pestaña A, Rey J A
Abstract excerpt
Formation of meningiomas and their progression to malignancy may be a multi-step process, implying accumulation of genetic mutations at specific loci. To determine the relationship between early NF2 gene inactivation and the molecular mechanisms that may contribute to meningioma tumor progression, we have performed deletion mapping analysis at chromosomes 1, 14 and 22 in a series of 81 sporadic meningiomas (54...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
