Article
Screening for mutations in the neurofibromatosis type 2 (NF2) gene in sporadic meningiomas.
Human genetics - 1 May 1996
De Vitis L R, Tedde A, Vitelli F, Ammannati F, Mennonna P, Bigozzi U, Montali E, Papi L
Abstract excerpt
Meningiomas are benign tumors of the central nervous system. They are usually sporadic but can also occur associated with the neurofibromatosis type 2 (NF2) syndrome. The gene responsible for NF2, recently isolated from chromosome 22, encodes a membrane-organizing protein that shows high sequence...
Topics
- Base Sequence
- Chromosome Deletion
- Chromosomes, Human, Pair 22
- DNA
- DNA Primers
- DNA, Neoplasm
- Exons
- Frameshift Mutation
- Genes, Neurofibromatosis 2
- Humans
- Introns
- Meningeal Neoplasms