Article
Mutational analysis of the NF2 gene in sporadic meningiomas by denaturing high-performance liquid chromatography.
International journal of molecular medicine - 1 Jul 2006
Kim Jae-Hong, Kim In-Soo, Kwon Sun-Young, Jang Byeong-Churl, Suh Seong-Il, Shin Dong-Hoon, Jeon Chang-Ho, Son Eun-Ik, Kim Sang-Pyo
Abstract excerpt
The NF2 tumor suppressor gene, located in chromosome 22q12, is involved in the development of sporadic meningiomas of the nervous system. In order to evaluate the role of the NF2 gene in sporadic meningiomas, we analyzed the entire coding regions of the NF2 gene in a group of 42 sporadic meningiomas: 17 meningothelial, 11 transitional, 11 fibrous, one secretory, one atypical, and one malignant subtype, using...
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