Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of the neurofibromatosis 2 gene reveals molecular variants of meningioma.

The American journal of pathology - 1 Apr 1995

Wellenreuther R, Kraus J A, Lenartz D, Menon A G, Schramm J, Louis D N, Ramesh V, Gusella J F, Wiestler O D, von Deimling A

Abstract excerpt

There is evidence from cytogenetic and loss of heterozygosity studies for the involvement of a tumor suppressor gene on chromosome 22 in the formation of meningiomas. Recently, the NF2 gene, which causes neurofibromatosis type 2 and which is located in the affected region on chromosome 22, has been identified. A previous study on 8 of the 17 exons of the NF2 gene described mutations in 16% of meningiomas. We have...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Base Sequence
Chromosomes, Human, Pair 22
Female
Genes, Neurofibromatosis 2
Humans
Male
Meningeal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Meningioma

Middle Aged

Molecular Sequence Data

Mutation

Polymorphism, Single-Stranded Conformational

Source

Open in PubMed Open full text

Identifiers

PMID: 7717450
PMCID: PMC1869258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7717450-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of the neurofibromatosis 2 gene reveals molecular variants of meningioma.PMID 7717450Read ↗

Screening for mutations in the neurofibromatosis type 2 (NF2) gene in sporadic meningiomas.Semantic proximity Read ↗

Inherited genetic syndromes and meningiomas.Semantic proximity Read ↗

Mutational analysis of the NF2 gene in sporadic meningiomas by denaturing high-performance liquid chromatography.Semantic proximity Read ↗

Predominant occurrence of somatic mutations of the NF2 gene in meningiomas and schwannomas.Semantic proximity Read ↗

Familial meningioma is not allelic to neurofibromatosis 2.Semantic proximity Read ↗

Neuropathology and Molecular Genetics of Neurofibromatosis 2 and Related TumorsSemantic proximity Read ↗

Combined molecular genetic studies of chromosome 22q and the neurofibromatosis type 2 gene in central nervous system tumors.Semantic proximity Read ↗

Lack of genetic and epigenetic changes in meningiomas without NF2 loss.Semantic proximity Read ↗

Mutational spectrum of the NF2 gene: a meta-analysis of 12 years of research and diagnostic laboratory findings.Semantic proximity Read ↗

Genetic and epigenetic alteration of the NF2 gene in sporadic meningiomas.Semantic proximity Read ↗

Frequent NF2 gene transcript mutations in sporadic meningiomas and vestibular schwannomas.Semantic proximity Read ↗

Deletions on chromosome 22 in sporadic meningiomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.