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Article

Allelic status of 1p, 14q, and 22q and NF2 gene mutations in sporadic schwannomas.

International journal of molecular medicine - 1 May 1998

Leone P E, Bello M J, Mendiola M, Kusak M E, De Campos J M, Vaquero J, Sarasa J L, Pestana A, Rey J A

Abstract excerpt

Schwannomas are common benign tumours of schwann cell origin, frequently found in patients with neurofibromatosis type 2 (NF2). Inactivation of the NF2 tumour suppressor gene appears to be a molecular event responsible for the development of up to 60% of cases, but no data are available on other...

Topics

Alleles
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 22
DNA Mutational Analysis
Genes, Neurofibromatosis 2
Genetic Markers
Humans
Loss of Heterozygosity
Mutation
Neurilemmoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

Source

Identifiers

PMID: 9852312
DOI: 10.3892/ijmm.1.5.889

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9852312-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Allelic status of 1p, 14q, and 22q and NF2 gene mutations in sporadic schwannomas.PMID 9852312Read ↗

NF2 gene mutations and allelic status of 1p, 14q and 22q in sporadic meningiomas.Semantic proximity Read ↗

Genetic and epigenetic alteration of the NF2 gene in sporadic meningiomas.Semantic proximity Read ↗

Screening for mutations in the neurofibromatosis type 2 (NF2) gene in sporadic meningiomas.Semantic proximity Read ↗

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Biallelic somatic inactivation of the NF1 gene through chromosomal translocations in a sporadic neurofibroma.Semantic proximity Read ↗

The neurofibromatosis type 2 gene is inactivated in schwannomasSemantic proximity Read ↗

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Ring chromosome 22 and neurofibromatosis type II: proof of two-hit model for the loss of the NF2 gene in the development of meningioma.Semantic proximity Read ↗

Interstitial loss and gain of sequences on chromosome 22 in meningiomas with normal karyotype.Semantic proximity Read ↗

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