Article
PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas.
Oncogene - 17 Feb 2005
Lee Jong Woo, Soung Young Hwa, Kim Su Young, Lee Hae Woo, Park Won Sang, Nam Suk Woo, Kim Sang Ho, Lee Jung Young, Yoo Nam Jin, Lee Sug Hyung
Abstract excerpt
A recent report revealed that phosphoinositide-3-kinase, catalytic, alpha (PIK3CA) gene is somatically mutated in several types of human cancer, suggesting the mutated PIK3CA gene as an oncogene in human cancers. However, because the previous report focused the mutational search primarily on colon cancers, the data on PIK3CA mutations in other types of human cancers have been largely unknown. Here, we performed...
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