Article
Mutation of the PIK3CA gene in ovarian and breast cancer.
Cancer research - 1 Nov 2004
Campbell Ian G, Russell Sarah E, Choong David Y H, Montgomery Karen G, Ciavarella Marianne L, Hooi Christine S F, Cristiano Briony E, Pearson Richard B, Phillips Wayne A
Abstract excerpt
Phosphatidylinositol 3'-kinases are lipid kinases with important roles in neoplasia. Recently, a very high frequency of somatic mutations in PIK3CA has been reported among a large series of colorectal cancers. However, the relevance of PIK3CA mutation in other cancer types remains unclear because...
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