Article
Oncogenic mutations of PIK3CA in human cancers.
Current topics in microbiology and immunology - 1 Jan 2010
Samuels Yardena, Waldman Todd
Abstract excerpt
The involvement of the PIK3CA gene product p110α, the catalytic subunit of phosphatidylinositol 3-kinase (PI3K), in human cancer has been suggested for over 15 years, and support for this proposal had been provided by both genetic and functional studies, including most recently the discovery of c...
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