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Article

Oncogenic mutations of PIK3CA in human cancers.

Cell cycle (Georgetown, Tex.) - 1 Oct 2004

Samuels Yardena, Velculescu Victor E

Abstract excerpt

Phosphatidylinositol 3-kinases (PI3Ks) are important regulators of signaling pathways. To determine whether PI3Ks are genetically altered in human cancers, we recently analyzed the sequences of the PI3K gene family and discovered that one member, the PIK3CA gene encoding the p110alpha catalytic s...

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Identifiers

PMID: 15467468
DOI: 10.4161/cc.3.10.1164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15467468-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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