Article
Caenorhabditis elegans gene ced-9 protects cells from programmed cell death.
Nature - 9 Apr 1992
Hengartner M O, Ellis R E, Horvitz H R
Abstract excerpt
The gene ced-9 of the nematode Caenorhabditis elegans acts to protect cells from programmed cell death. A mutation that abnormally activates ced-9 prevents the cell deaths that occur during normal C. elegans development. Conversely, mutations that inactivate ced-9 cause cells that normally live to undergo programmed cell death; these mutations result in embryonic lethality, indicating that ced-9 function is...
Topics
- Animals
- Caenorhabditis
- Cell Death
- Gene Expression Regulation
- Genes, Lethal
- Genotype
- Mutation
- Phenotype