Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities.

Genes & development - 1 Mar 1996

Shaham S, Horvitz H R

Abstract excerpt

We developed a method for examining the effects of overexpressing cell-death-related genes in specific Caenorhabditis elegans neurons that normally live. Using this method, we demonstrated that the cell-death genes ced-3, ced-4, and ced-9 all can act cell autonomously to control programmed cell death. Our observations indicate further that not only the protective activity of ced-9 but also the killer activities...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Base Sequence
Share to Cell Survival

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Molecular Sequence Data

Share to Mutation

Share to Neurons

Share to Proto-Oncogene Proteins

Source

Identifiers

PMID: 8598288
DOI: 10.1101/gad.10.5.578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities.PMID 8598288Read ↗

The ins and outs of programmed cell death during C. elegans development.Semantic proximity Read ↗

An alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitor.Semantic proximity Read ↗

Noncanonical cell death programs in the nematode Caenorhabditis elegans.Semantic proximity Read ↗

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death.Semantic proximity Read ↗

Programmed cell deathSemantic proximity Read ↗

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death.Semantic proximity Read ↗

Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegans.Semantic proximity Read ↗

Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans.Semantic proximity Read ↗

The ced-8 gene controls the timing of programmed cell deaths in C. elegans.Semantic proximity Read ↗

eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans.Semantic proximity Read ↗

Caenorhabditis elegans genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33.Semantic proximity Read ↗

Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.