Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities.

doi:10.1101/gad.10.5.578

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Article

Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities.

Genes & development - 1 Mar 1996

Shaham S, Horvitz H R

Abstract excerpt

We developed a method for examining the effects of overexpressing cell-death-related genes in specific Caenorhabditis elegans neurons that normally live. Using this method, we demonstrated that the cell-death genes ced-3, ced-4, and ced-9 all can act cell autonomously to control programmed cell d...

Topics

Animals
Animals, Genetically Modified
Apoptosis
Apoptosis Regulatory Proteins
Base Sequence
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Calcium-Binding Proteins
Caspases
Cell Survival
Genes, Helminth
Helminth Proteins
Models, Genetic
Molecular Sequence Data
Mutation
Neurons
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-bcl-2

Source

Open in PubMed

Identifiers

PMID: 8598288
DOI: 10.1101/gad.10.5.578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8598288-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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