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Article

Noncanonical cell death programs in the nematode Caenorhabditis elegans.

Cell death and differentiation - 1 Jul 2008

Blum E S, Driscoll M, Shaham S

Abstract excerpt

Genetic studies of the nematode Caenorhabditis elegans have uncovered four genes, egl-1 (BH3 only), ced-9 (Bcl-2 related), ced-4 (apoptosis protease activating factor-1), and ced-3 (caspase), which function in a linear pathway to promote developmental cell death in this organism. While this core pathway functions in many cells, recent studies suggest that additional regulators, acting on or in lieu of these core...

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PMID: 18437162
DOI: 10.1038/cdd.2008.56

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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