Article
The ced-8 gene controls the timing of programmed cell deaths in C. elegans.
Molecular cell - 1 Mar 2000
Stanfield G M, Horvitz H R
Abstract excerpt
Loss-of-function mutations in the gene ced-8 lead to the late appearance of cell corpses during embryonic development in C. elegans. ced-8 functions downstream of or in parallel to-the regulatory cell death gene ced-9 and may function as a cell death effector downstream of the caspase encoded by the programmed cell death killer gene ced-3. In ced-8 mutants, embryonic programmed cell death probably initiates...
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