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Article

Ctla4 and multiple sclerosis in the Italian population.

Experimental and molecular pathology - 1 Feb 2005

Malferrari G, Stella A, Monferini E, Saltini G, Proverbio M C, Grimaldi L M, Rossi-Bernardi L, Biunno I

Abstract excerpt

CTLA4 protein is a receptor molecule that plays a critical role as a negative regulator of the immune response. Therefore, genetic variations in CTLA4 may confer susceptibility to autoimmune diseases such as multiple sclerosis (MS). In order to investigate the association of two CTLA4 polymorphisms (+49 A/G and -318 C/T) with multiple sclerosis, sporadic MS patients and healthy controls from Italy were genotyped...

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Source

Identifiers

PMID: 15596061
DOI: 10.1016/j.yexmp.2004.10.001

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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