Article
CTLA4 exon 1 and promoter polymorphisms in patients with multiple sclerosis.
Acta neurologica Scandinavica - 1 Dec 2009
Yousefipour G, Erfani N, Momtahan M, Moghaddasi H, Ghaderi A
Abstract excerpt
OBJECTIVE: The polymorphisms of exon 1 (+49 A/G) and promoter regions (-1722 T/C, -1661 A/G and -318 C/T)of cytotoxic T lymphocyte antigen 4 (CTLA4) and also haplotypes constructed from mentioned loci were investigated amongst 153 Iranian patients with definite multiple sclerosis (MS) and 190 healthy controls. METHODS: The polymorphisms were genotyped by PCR-restriction fragment length polymorphisms and...
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