Article
Some Common SNPs of the T-Cell Homeostasis-Related Genes Are Associated with Multiple Sclerosis, but Not with the Clinical Manifestations of the Disease, in the Polish Population.
Journal of immunology research - 1 Jan 2020
Chorąży Monika, Wawrusiewicz-Kurylonek Natalia, Adamska-Patruno Edyta, Zajkowska Olga, Kapica-Topczewska Katarzyna, Posmyk Renata, Krętowski Adam Jacek, Kochanowicz Jan, Kułakowska Alina
Abstract excerpt
PURPOSE: Multiple sclerosis (MS) is an autoimmune disease, and genetic factors play an important role in its pathogenesis and progression. The aim of our study was to evaluate the frequencies of alleles and genetic variants of the T-cell homeostasis-related genes, in subjects with MS, as well as to investigate the association with MS clinical manifestations and disability. METHODS: 94 subjects with MS and 160...
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