Article
TLR4 haplotypes in multiple sclerosis: a case-control study in the Spanish population.
Journal of neuroimmunology - 1 Dec 2007
Urcelay Elena, Blanco-Kelly Fiona, de Las Heras Virginia, de la Concha Emilio G, Arroyo Rafael, Martínez Alfonso
Abstract excerpt
Our aim in the present study is to evaluate the variation present in the TLR4 gene and its relationship with multiple sclerosis susceptibility in the Spanish population. Three hundred and sixty-two multiple sclerosis patients and 467 healthy controls from the Spanish population were included in the present study. Twelve single nucleotide polymorphisms (SNPs) were selected, and analyzed by the TaqMan technique. No...
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