Article
CTLA-4 gene polymorphisms (-318C/T, +49A/G, +6230A/G) in Iranian patients with multiple sclerosis.
Iranian journal of allergy, asthma, and immunology - 1 Dec 2010
Heidari Abolfazl, Noori Daloii Mohammad Reza, Keramatipour Mohammad, Rashikinezhad Ali, Sahmani Ahmad Ali, Amirzargar Ali Akbar
Abstract excerpt
Multiple sclerosis (MS) is a disease of the central nervous system (CNS) characterized by multiple regions of demyelination and inflammation along axons with a T cell-mediated autoimmune etiology. While the cytotoxic T lymphocyte antigen 4 (CTLA-4) gene seems to be a strong candidate gene in auto...
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