Article
Oncogenic derivatives of platelet-derived growth factor receptors.
Cellular and molecular life sciences : CMLS - 1 Dec 2004
Jones A V, Cross N C P
Abstract excerpt
Platelet-derived growth factor receptors (PDGFRs) and their ligands, platelet-derived growth factors (PDGFs) play critical roles in mesenchymal cell migration and proliferation. In embryogenesis the PDGFR/PDGF system is essential for the correct development of the kidney, cardiovascular system, brain, lung and connective tissue. In adults, PDGFR/PDGF is important in wound healing, inflammation and angiogenesis....
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