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Article

PDGF receptors as targets in tumor treatment.

Advances in cancer research - 1 Jan 2007

Ostman Arne, Heldin Carl-Henrik

Abstract excerpt

Signaling through platelet-derived growth factor (PDGF) receptors contributes to multiple tumor-associated processes. The recent introduction of clinically useful PDGF inhibitors have the last years validated PDGF receptors in malignant and stromal cells as relevant cancer drug targets. Mutational activation of PDGF receptor signaling in malignant cells has been described in some rare tumor types such as...

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PMID: 17419949
DOI: 10.1016/S0065-230X(06)97011-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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