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Functional and clinical roles of stromal PDGF receptors in tumor biology

9 Jul 2024

Abstract excerpt

PDGF receptors play pivotal roles in both developmental and physiological processes through the regulation of mesenchymal cells involved in paracrine instructive interactions with epithelial or endothelial cells. Tumor biology studies, alongside analyses of patient tissue samples, provide strong indications that the PDGF signaling pathways are also critical in various types of human cancer. This review summarizes...

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PMID: 38980580
DOI: 10.1007/s10555-024-10194-7

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