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Article

Non-equivalent interactions between amino-terminal domains of neighboring lambda integrase protomers direct Holliday junction resolution.

Journal of molecular biology - 21 Jan 2005

Lee Sang Yeol, Radman-Livaja Marta, Warren David, Aihara Hideki, Ellenberger Tom, Landy Arthur

Abstract excerpt

The bacteriophage lambda site-specific recombinase (Int), in contrast to other family members such as Cre and Flp, has an amino-terminal domain that binds "arm-type" DNA sequences different and distant from those involved in strand exchange. This defining feature of the heterobivalent recombinases confers a directionality and regulation that is unique among all recombination pathways. We show that the...

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Identifiers

PMID: 15581892
DOI: 10.1016/j.jmb.2004.10.068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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