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Article

Minimal mutational requirements for conversion of a telomere resolvase into a Cre-like site-specific recombinase.

PloS one - 1 Jan 2026

Huang Shu Hui, Kobryn Kerri

Abstract excerpt

Hairpin telomere resolvases comprise a family of enzymes that produce the hairpin (hp) telomeres of bacteria and their phages that possess linear chromosomes and plasmids terminated by covalently closed hp telomeres. The hp telomeres overcome the dual issues of end replication and protection faced by all organisms with linear genomes. The hp telomeres are produced from replicated intermediates in which the hp...

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Identifiers

PMID: 42213814
DOI: 10.1371/journal.pone.0350834
PMCID: PMC13221069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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