Article
Coordinated control of XerC and XerD catalytic activities during Holliday junction resolution.
Journal of molecular biology - 2 Jun 2000
Arciszewska L K, Baker R A, Hallet B, Sherratt D J
Abstract excerpt
Site-specific recombinases XerC and XerD function in the segregation of circular bacterial replicons. In a recombining nucleoprotein complex containing two molecules each of XerC and XerD, coordinated reciprocal switches in recombinase activity ensure that only XerC or XerD is active at any one time. Mutated recombinases that carry sub?stitutions of a catalytic arginine residue stimulate cleavage and strand...
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