Article
Interactions between lambda Int molecules bound to sites in the region of strand exchange are required for efficient Holliday junction resolution.
Journal of molecular biology - 20 Oct 1990
Franz B, Landy A
Abstract excerpt
lambda Site-specific recombination proceeds via two sequential single-strand exchanges that first generate and then resolve a Holliday recombination intermediate. The resolution of artificial Holliday junctions (chi-forms) is well suited to studying the mechanisms involved in reciprocal strand ex...
Topics
- Bacteriophage lambda
- Base Sequence
- Binding Sites
- Cloning, Molecular
- Consensus Sequence
- DNA Nucleotidyltransferases
- DNA, Viral
- Integrases
- Models, Genetic
- Molecular Sequence Data
- Mutation
- Plasmids
- Recombination, Genetic
- Viral Core Proteins