Article
Architectural flexibility in lambda site-specific recombination: three alternate conformations channel the attL site into three distinct pathways.
Genes to cells : devoted to molecular & cellular mechanisms - 1 May 1996
Segall A M, Nash H A
Abstract excerpt
BACKGROUND: In the phage lambda life cycle, the Integrase (Int) protein carries out recombination between two different sets of DNA substrates: attP and attB in integration, attL and attR in excision. In each case, the partners are very different in structure from each other and the recombination reaction between them is effectively irreversible. For comparison, we have studied the recombination mediated by Int...
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