Article
Architectural flexibility in lambda site-specific recombination: three alternate conformations channel the attL site into three distinct pathways.
Genes to cells : devoted to molecular & cellular mechanisms - 1 May 1996
Segall A M, Nash H A
Abstract excerpt
BACKGROUND: In the phage lambda life cycle, the Integrase (Int) protein carries out recombination between two different sets of DNA substrates: attP and attB in integration, attL and attR in excision. In each case, the partners are very different in structure from each other and the recombination...
Topics
- Attachment Sites, Microbiological
- Bacteriophage lambda
- Base Sequence
- DNA, Bacterial
- DNA, Viral
- Integrases
- Mutation
- Nucleic Acid Conformation
- Phenotype
- Recombination, Genetic
- Substrate Specificity