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The λ Integrase Site-specific Recombination Pathway

2 Apr 2015

Abstract excerpt

The site-specific recombinase encoded by bacteriophage λ (Int) is responsible for integrating and excising the viral chromosome into and out of the chromosome of its Escherichia coli host. Int carries out a reaction that is highly directional, tightly regulated, and depends upon an ensemble of accessory DNA bending proteins acting on 240 bp of DNA encoding 16 protein binding sites. This additional complexity...

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PMID: 26104711
DOI: 10.1128/microbiolspec.mdna3-0051-2014

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