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Differentiation of human embryonic stem cells to dopaminergic neurons in serum-free suspension culture.

Stem cells (Dayton, Ohio) - 1 Jan 2004

Schulz Thomas C, Noggle Scott A, Palmarini Gail M, Weiler Deb A, Lyons Ian G, Pensa Kate A, Meedeniya Adrian C B, Davidson Bruce P, Lambert Nevin A, Condie Brian G

Abstract excerpt

The use of human embryonic stem cells (hESCs) as a source of dopaminergic neurons for Parkinson's disease cell therapy will require the development of simple and reliable cell differentiation protocols. The use of cell cocultures, added extracellular signaling factors, or transgenic approaches to drive hESC differentiation could lead to additional regulatory as well as cell production delays for these therapies....

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Identifiers

PMID: 15579641
DOI: 10.1634/stemcells.2004-0114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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