Article
Induction of human mesenchymal stem cells into dopamine-producing cells with different differentiation protocols.
Stem cells and development - 1 Jun 2008
Barzilay Ran, Kan Inna, Ben-Zur Tali, Bulvik Shlomo, Melamed Eldad, Offen Daniel
Abstract excerpt
Several reports have shown that human mesenchymal stem cells (MSCs) are capable of differentiating outside the mesenchymal lineage. We sought to induce MSCs to differentiate into dopamine-producing cells for potential use in autologous transplantation in patients with Parkinson's disease (PD). Following cell culture with various combinations of differentiation agents under serum-free defined conditions, different...
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