Article
In vitro assays for neural stem cell differentiation: induction of dopaminergic phenotype.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008
Daadi Marcel M
Abstract excerpt
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra. Symptoms include tremors, rigidity, bradykinesia, and instability. Neural transplantation is a promising strategy for improving dopaminergic dysfunction in PD provided that the dopaminergic neurons are consistently generated from a renewable source of cells. Neural stem cells (NSCs)...
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