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Article

Derivation of midbrain dopamine neurons from human embryonic stem cells.

Proceedings of the National Academy of Sciences of the United States of America - 24 Aug 2004

Perrier Anselme L, Tabar Viviane, Barberi Tiziano, Rubio Maria E, Bruses Juan, Topf Norbert, Harrison Neil L, Studer Lorenz

Abstract excerpt

Human embryonic stem (hES) cells are defined by their extensive self-renewal capacity and their potential to differentiate into any cell type of the human body. The challenge in using hES cells for developmental biology and regenerative medicine has been to direct the wide differentiation potential toward the derivation of a specific cell fate. Within the nervous system, hES cells have been shown to differentiate...

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Identifiers

PMID: 15310843
DOI: 10.1073/pnas.0404700101
PMCID: PMC515094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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