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Article

Stem cell‐based therapy for Parkinson's disease

1 Jan 2005

Abstract excerpt

Motor dysfunctions in Parkinson's disease are considered to be primarily due to the degeneration of dopaminergic neurons in the substantia nigra pars compacta. Pharmacological therapies based on the principle of dopamine replacement are extremely valuable, but suffer from two main drawbacks: troubling side effects (e.g. dyskinesia) and loss of efficacy with disease progression. Transplantation of embryonic...

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PMID: 16278162
DOI: 10.1080/07853890500327967

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