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Article

Toll-like receptor 4 Asp299Gly gene polymorphism and risk of atherothrombosis.

Stroke - 1 Jan 2005

Zee Robert Y L, Hegener Hillary H, Gould Jessica, Ridker Paul M

Abstract excerpt

BACKGROUND AND PURPOSE: Recent findings of an association between a functional toll-like receptor 4 (TLR4) D299G gene variant and reduced risk of atherothrombotic disorders have generated great interest. METHODS: We evaluated the TLR4 D299G polymorphism among 695 individuals with incident myocardial infarction (MI) or stroke and among 695 age- and smoking-matched individuals who remained free of reported...

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Source

Identifiers

PMID: 15576653
DOI: 10.1161/01.STR.0000149948.31879.f0

Genes

TLR4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Toll-like receptor 4 Asp299Gly gene polymorphism and risk of atherothrombosis.PMID 15576653Read ↗

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Toll-like receptor 4 gene Asp299Gly polymorphism in myocardial infarction: a meta-analysis of 15,148 subjects.Semantic proximity Read ↗

Toll-like receptor 4 gene polymorphisms and myocardial infarction: no association in a Caucasian population.Semantic proximity Read ↗

Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.Semantic proximity Read ↗

Toll-like receptor 4 gene polymorphisms show no association with the risk of clinical or angiographic restenosis after percutaneous coronary intervention.Semantic proximity Read ↗

Variation in the toll-like receptor 4 gene and susceptibility to myocardial infarction.Semantic proximity Read ↗

Lack of association between TLR4 Asp299Gly polymorphism and atherosclerosis: evidence from meta-analysis.Semantic proximity Read ↗

Toll-like receptor 4 gene polymorphisms and acute coronary syndrome: no association in a Mexican population.Semantic proximity Read ↗

Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes.Semantic proximity Read ↗

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TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis.Semantic proximity Read ↗

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