Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis.

Atherosclerosis - 1 Sept 2003

Yang Ian A, Holloway John W, Ye Shu

Abstract excerpt

UNLABELLED: Inflammation and innate immunity may play a role in the pathogenesis of atherosclerosis. The Asp299Gly polymorphism in the toll-like receptor 4 (TLR4) gene reduces responsiveness to lipopolysaccharide and has been associated with reduced incidence and slower progression of carotid atherosclerosis. We analyzed this polymorphism in relation to susceptibility to and severity of coronary artery disease....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Stenosis
Share to Logistic Models
Share to Membrane Glycoproteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Receptors, Cell Surface

Share to Severity of Illness Index

Share to Statistics as Topic

Share to Toll-Like Receptor 4

Share to Toll-Like Receptors

Source

Identifiers

PMID: 12957699
DOI: 10.1016/s0021-9150(03)00286-7

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis.PMID 12957699Read ↗

Lack of association between TLR4 Asp299Gly polymorphism and atherosclerosis: evidence from meta-analysis.Semantic proximity Read ↗

Toll-like receptor-4 Asp299Gly polymorphism does not influence progression of atherosclerosis in patients with familial hypercholesterolaemia.Semantic proximity Read ↗

Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.Semantic proximity Read ↗

Association between Toll-like receptor 4 Asp299Gly polymorphism and coronary heart disease susceptibility.Semantic proximity Read ↗

Toll-like receptor 4 gene polymorphisms and acute coronary syndrome: no association in a Mexican population.Semantic proximity Read ↗

The Asp299Gly Toll-like receptor 4 polymorphism in advanced aortic atherosclerosis.Semantic proximity Read ↗

Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes.Semantic proximity Read ↗

Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events.Semantic proximity Read ↗

Toll-like receptor 4 gene Asp299Gly polymorphism in myocardial infarction: a meta-analysis of 15,148 subjects.Semantic proximity Read ↗

Lack of association between polymorphisms of the toll-like receptor 4 gene and cerebral ischemia.Semantic proximity Read ↗

Toll-like receptor 8 polymorphism and coronary artery disease.Semantic proximity Read ↗

Effect of the Toll-like receptor 4 (TLR-4) variants on intima-media thickness and monocyte-derived macrophage response to LPS.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.