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Article

Variation in the toll-like receptor 4 gene and susceptibility to myocardial infarction.

Pharmacogenetics and genomics - 1 Jan 2005

Holloway John W, Yang Ian A, Ye Shu

Abstract excerpt

Variation in the gene encoding toll-like receptor 4 (TLR4), a transmembrane receptor that mediates inflammatory responses to bacterial endotoxin, has been associated with susceptibility to atherosclerosis and its complications, such as myocardial infarction (MI), the pathogenesis of which involve...

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Source

Identifiers

PMID: 15864121
DOI: 10.1097/01213011-200501000-00003

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15864121-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Variation in the toll-like receptor 4 gene and susceptibility to myocardial infarction.PMID 15864121Read ↗

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Association between Toll-like receptor 4 Asp299Gly polymorphism and coronary heart disease susceptibility.Semantic proximity Read ↗

The effect of genetic polymorphisms of TLR2 and TLR4 in Turkish patients with coronary artery disease.Semantic proximity Read ↗

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Toll-like receptor 4 Asp299Gly gene polymorphism and risk of atherothrombosis.Semantic proximity Read ↗

Interleukin-6 gene polymorphisms and susceptibility to myocardial infarction: the ECTIM study. Etude Cas-Témoin de l'Infarctus du Myocarde.Semantic proximity Read ↗

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