Article
Toll-like receptor (TLR)-9 promotor polymorphisms and atherosclerosis.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2006
Hamann Lutz, Glaeser Christiane, Hamprecht Axel, Gross Michael, Gomma Abuzeid, Schumann Ralf R
Abstract excerpt
BACKGROUND: Currently, the primary cause of atherosclerosis remains controversial: while oxidized or enzymatically altered LDL is widely accepted as one cause of the inflamed lesion, microorganisms such as C. pneumoniae or cytomegalovirus (CMV) also have recently been postulated to be involved in the pathogenesis of atherosclerosis. Microbial products activate innate immune cells of the host via Toll-like...
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