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Article

Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2003

Ameziane Nejma, Beillat Tiphaine, Verpillat Patrice, Chollet-Martin Sylvie, Aumont Marie-Claude, Seknadji Patrick, Lamotte Maryse, Lebret Dominique, Ollivier Véronique, de Prost Dominique

Abstract excerpt

OBJECTIVE: Atherosclerosis is a chronic inflammatory disease of the blood vessels. Toll-like receptor 4 (TLR4) is a transmembrane receptor that is involved in mediating inflammatory responses to bacterial endotoxin and other ligands. The aim of this study was to search for an association between a common functional polymorphism of TLR4--Asp299Gly--and acute coronary syndrome. METHODS AND RESULTS: We conducted a...

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Source

Identifiers

PMID: 14563652
DOI: 10.1161/01.ATV.0000101191.92392.1D

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.PMID 14563652Read ↗

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