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Article

Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction.

European heart journal - 1 Aug 2004

Edfeldt Kristina, Bennet Anna M, Eriksson Per, Frostegård Johan, Wiman Björn, Hamsten Anders, Hansson Göran K, de Faire Ulf, Yan Zhong-qun

Abstract excerpt

AIM: Toll-like receptor 4 (TLR4) is a receptor for bacterial lipopolysaccharide (LPS) and heat shock protein essential for innate immunity. Recent studies imply that TLR4 polymorphisms might affect atherogenesis. In this study we investigated the impact of LPS-hypo-responsive TLR4 variants on the risk of myocardial infarction (MI). METHODS AND RESULTS: Using TaqMan PCR technology, we determined the prevalence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15302104
DOI: 10.1016/j.ehj.2004.05.004

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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