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Article

Homozygous and heterozygous CCR5-Delta32 genotypes are associated with resistance to HIV infection.

Journal of acquired immune deficiency syndromes (1999) - 15 Aug 2001

Marmor M, Sheppard H W, Donnell D, Bozeman S, Celum C, Buchbinder S, Koblin B, Seage G R

Abstract excerpt

OBJECTIVE: To investigate evidence for resistance to HIV-1 infection associated with the heterozygous genotype CCR5-+/Delta32 and with the homozygous genotype CCR5-Delta32/Delta32, which results in a nonfunctional CCR5 receptor. DESIGN: Cohort study of initially HIV-seronegative high-risk individuals from eight different cities. Enrollment data were analyzed to investigate the association of demographic factors...

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Source

Identifiers

PMID: 11511825
DOI: 10.1097/00126334-200108150-00009

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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